ASST RESEARCH SCIENTIST/ENGINRequisition # 72839Position BasicsWorking TitleASSISTANT RESEARCH SCIENTISTAdvertising Ends on:Wednesday, May 30th, 2018Advertising Started on:Wednesday, May 16th, 2018Organization:Carver College of MedicineDepartment:Internal MedicineSalarySalary:$48,546.00 to CommensuratePay Grade:5AJob DetailsPercent Time:100%Type of PositionSpecified Term: A staff member may be appointed to term status for a specific term not to exceed three years in order to accomplish a specific purpose or when the duration of funding is limited or unknown.Duties:Conduct highly technical and specialized scientific research in studying genes influencing cardiovascular disease by independently securing funding; performing research experiments, simulations and theoretical investigations; analyzing data; and disseminating research findings. Key areas of responsibility include experiments, simulations, modeling or theoretical investigations; data/research analysis and evaluation; dissemination of research results; research proposals/grants; service; and human resources/supervision. Duties will include design and execution of experiments, performing mouse surgeries for generating cardiac hypertrophy and heart failure models, intravenous injections, molecular and biochemical analyses of gene/protein expression, assessment of tissue pathology, data analyses and presentation, preparation of manuscripts and grant applications.Education Required:A Doctoral degree in Molecular and Cellular Biology, cardiovascular sciences, or related discipline is required.Experience Required:1-3 years of heart disease research is required.Excellent written and verbal communication skills are required.Experience establishing and maintaining in vitro cell culture models, transfection and RNAi application, and standard molecular cloning techniques is required.Record of peer-reviewed publications in the field is required.Technical expertise with transverse aortic constriction (TAC) surgery and jugular/temporal vein injections in mice is required.Experience with dissection and harvest of heart and/or other tissues is required.RNA and protein isolation and analyses (Q-PCR, western blot) is required.Experience with Microsoft Word, PowerPoint and Excel, Adobe Photoshop, and Adobe Illustrator is required.Experience trouble-shooting protocols, statistically analyzing data, teaching and supervising lab personnel in various techniques, and writing peer-reviewed manuscripts and grant applications is required.Experience with neonatal or adult cardiomyocyte isolation from small animals is required.Experience with tissue processing and staining (cyrosectioning, IHC, IF, confocal microscopy), mitochondria isolation and functional analyses (Seahorse, calcium uptake), testing of mouse phenotypes (EKG, GTT, ITT) is required.Desirable Qualifications:Experience with use of adeno-associated virus vectors, genotyping and maintaining mouse colonies is highly desirable.Knowledge of University of Iowa Health Care policies and procedures is desirable.Online Application OptionsApplication Type:This job requires a full online application.Cover Letter:A plain text cover letter is required.References:References must be filled out online during the application process, however, only professional references will be allowed.Number of References: 3To start the Online Application process for this position, click the "Apply for This Position" button located below the Contact Information.Contact InformationContact:Stacy M Pruter - intmed-hr-apps@uiowa.eduCmed-Internal MedicineGeneral Hospital220 Hawkins DriveSE322 GHIowa City, IA 52242For information about applying for P&S positions, please go toProfessional and Scientific Position Application ProceduresThe qualifications for the positions are listed in the job advertisement.Equivalent combinations of education and related work experience may be considered. The salary listed indicates the minimum for the pay grade to a level commensurat